The primary ingredient of Angard, Setria™ Glutathione, developed by Kyowa, is a form of L-Glutathione or reduced glutathione, which is the active structure ready to donate electrons to free radicals (1). A 6-month clinical study with 54 non-smokers showed that 1,000 mg/day of Setria™ significantly increased blood glutathione levels and doubled Natural Killer cell activity after three months, demonstrating its potent immune-boosting effects (2). Glutathione, known as a 'super antioxidant,' not only neutralizes free radicals but also activates other antioxidants like vitamins E and C, contributing to their recycling processes (3). It plays a crucial role in the body's natural detoxification by supporting liver and kidney functions and neutralizing toxins before absorption (4). Selenium, another key ingredient, acts as a powerful antioxidant, integral to the function of various glutathione peroxidases. It helps in reusing oxidized glutathione and strengthens the immune system, also offering protection against certain cancers and heart diseases (5, 6, 7). Riboflavin 5'-phosphate (R5P) is included to enhance vitamin B2 metabolism, especially important for individuals with MTHFR gene mutations. R5P improves the functioning of this metabolism and increases the phagocytic activity of neutrophils and macrophages, vital for immune response (8 , 9). Molybdenum acts as a cofactor for several crucial enzymes like sulfite oxidase and xanthine oxidase, necessary for toxin removal from the body (10). Lastly, Pyrroloquinoline Quinone (PQQ) is incorporated for its exceptional antioxidant activity, surpassing vitamin C by 100 times (11). It protects various organelles, including mitochondria, from oxidative stress and promotes the formation of new mitochondria, thereby enhancing energy production (12).
Together, these ingredients make Angard a powerful supplement for enhancing immune function, supporting detoxification, and promoting overall cellular health and energy production.
Cognizant stands out as a meticulously formulated cognitive enhancer, blending key ingredients backed by scientific research. Vitamin B6 plays a crucial role in this blend, addressing deficiencies linked to Alzheimer's and dementia (1). Ginkgo biloba, another integral component, is lauded for its potential in assisting memory disorders, cognitive speed, and symptoms related to traumatic brain injury (TBI), Alzheimer's dementia, and stroke, due to its neuroprotective and antioxidant properties (2). Tyrosine, also included, is recognized for enhancing alertness in conditions like Phenylketonuria (PKU), improving mental performance, memory, and attention in various scenarios including ADHD, narcolepsy, and sleep deprivation (3). The formula is further enriched with 500mg of Cognizin®, which has been shown to boost brain energy and membrane formation, with studies in adults indicating enhanced frontal lobe bioenergetics (4). In trials with healthy, middle-aged women, Cognizin has demonstrated improvements in attention and reduced error rates (5). Lastly, the inclusion of 100 mg of phosphatidylserine in the daily regimen has been clinically proven to sustain cognitive function improvements even three months post-usage, specifically in elderly subjects with memory complaints (6). Cognizant, therefore, emerges as a potent solution for those seeking to boost cognitive functions, memory, and overall mental alertness, making it an ideal choice for a broad spectrum of users aiming to enhance their cognitive health.
Our food supplement Rhodiolin is harnessing the power of adaptogenic herbs to bolster the body's resistance to stress. Central to its formulation is Rhodiola, an herb celebrated for its ability to normalize stress hormone release and enhance energy production, as underscored in studies focused on stress management (1). Rhodiola is not only effective in mitigating psychological and physiological stress, but it also boasts anti-inflammatory and antioxidant properties, offering protective benefits against heart and brain diseases, including heart attacks and Alzheimer's. Its efficacy extends to improving general mood, reducing mental fatigue, and alleviating symptoms associated with stress and anxiety, including anger and confusion (2). Additionally, Rhodiolin includes glycine, a key component known for its diverse benefits: boosting glutathione (3) and creatine production (4), supporting collagen (5), enhancing heart health (6), and providing calming effects (7). Furthermore, the inclusion of L-Theanine in Rhodiolin's formula is pivotal. Clinical studies have validated its role in improving emotional states (8), reducing anxiety and stress (9), enhancing mood and cognition (10), and preventing cognitive impairment through its antioxidant and anti-inflammatory activity in the brain, especially when paired with caffeine (11). Together, these ingredients in Rhodiolin create a synergistic blend that addresses various aspects of mental well-being, making it an exemplary choice for those seeking natural support in managing stress, enhancing cognitive functions, and promoting overall health.
Magna P, featuring a blend of magnesium malate, magnesium citrate, magnesium bisglycinate, and magnesium taurate, offers a range of clinically proven benefits that address several health concerns. Magnesium deficiency has been linked to depression and anxiety, with studies demonstrating the anxiolytic effects of magnesium in both animal models and human clinical trials (1). Each form of magnesium in your product targets specific health issues effectively. Magnesium malate is known for its role in energy metabolism, making it beneficial for individuals experiencing fatigue. Magnesium citrate is often recommended for its bioavailability and effectiveness in improving digestive health and preventing migraines. Magnesium taurate, combining magnesium with taurine, is particularly beneficial for heart health and in managing symptoms of insulin resistance (2). Moreover, magnesium bisglycinate, known for its high absorption rate and gentleness on the stomach, is particularly effective in reducing anxiety and regulating sleep patterns when taken before bedtime. It's also used in the treatment of depression, showcasing its significant impact on mental health (3). Together, these forms of magnesium offer a comprehensive approach to improving overall health. They support migraine relief, enhance energy metabolism, aid in managing insulin resistance, and have a calming effect on the nervous system, making your product a versatile supplement for those seeking to address a wide range of health issues through natural means.
Brokolive is a supplement that combines a range of natural ingredients, each with significant clinical evidence supporting their health benefits. The supplement's key component, glucoraphanin, is converted into sulforaphane (SF) in the intestine by the myrosinase enzyme. Sulforaphane is a powerful phytochemical, renowned for its chemoprotective properties. It activates phase II enzymes like quinone reductase and heme oxygenase I, which are essential in protecting cells from carcinogens, reactive oxygen species, toxins, and cellular damage. This process plays a crucial role in enhancing the body's natural defense mechanisms against various forms of cellular stress (1). Furthermore, these phase II enzymes are responsible for maintaining a balance between reactive oxygen species and glutathione, a key antioxidant in the body, thereby supporting overall cellular health (2). Alpha GPC, another vital ingredient in Brokolive, supports kidney and liver functions, contributing to their regeneration and detoxification processes. This highlights its importance in maintaining organ health and facilitating the body's natural detoxification pathways (3). Silymarin, derived from milk thistle, offers notable hepatoprotective effects. It works through antioxidant activity, neutralizing free radicals, increasing cellular glutathione levels, stimulating DNA polymerase, and stabilizing the hepatocellular membrane. These actions help protect the liver from various forms of damage and support its vital detoxification role (4). Artichoke extract, known for its ability to inhibit cholesterol biosynthesis and LDL oxidation, enhances fat metabolism and vitamin absorption by regulating bile secretion. Additionally, it aids in blood sugar level regulation, contributing to metabolic health (5). Lastly, dandelion, rich in flavonoids, enhances bile fluidity, aiding in the elimination of toxins and potentially offering protection against the development of liver cancer (6). Brokolive, with its blend of glucoraphanin, Alpha GPC, silymarin, artichoke extract, and dandelion, emerges as a comprehensive supplement for enhancing detoxification, protecting against cellular damage, and supporting liver and kidney health.
Serenita, a revolutionary product in the realm of natural sleep aids and anxiety relief, incorporates a potent blend of clinically proven ingredients. Valerian root, with dosages ranging from 160-600 mg daily, has been substantiated to enhance sleep quality, shorten wake-up recovery time, and improve overall sleep time and insomnia intensity, as highlighted in various studies (1). Additionally, M. Chamomilla is recognized for its sedative and anxiolytic properties, attributed to its modulation of GABA receptors (2). This has been particularly evident in patients with general anxiety disorder, where significant reductions in accompanying anxiety and depression were noted (3). Furthermore, hops extract, rich in terpenoids and flavonoids like humulene and myrkene (4), is utilized in modern medicine for its efficacy in alleviating anxiety and insomnia, with clinical trials demonstrating notable anxiety level reductions (5). Lemon balm extract, another key component, has shown promising results in decreasing insomnia and mild to moderate anxiety by 15-42% (6). Lastly, Passiflora extract is renowned for its anxiety-soothing effects through the GABA mechanism, underscoring its potential in managing anxiety disorders (7). Together, these ingredients synergistically work to offer a comprehensive solution for those seeking natural relief from sleep disturbances and anxiety.